Publications:

Book chapters


  • TJ MacCormack, GG Goss, and RD Handy. Emerging threats: Engineered organic nanomaterials. In: Organic Chemical Toxicology of Fishes, volume 33 in the Fish Physiology series. Edited by K Tierney, AP Farrell, and CJ Brauner.Elsevier, London. 

Comparative Biochemistry and Toxicology

Peer-reviewed papers

  1. EF Henry, TJ MacCormack. Taurine protects cardiac contractility in Fundulus heteroclitus by enhancing sarcoplasmic reticular Ca2+ cycling. J Comp Physiol B,  in press JCPB-D-17-00009.
  2. JC Capaz, L Tunnah, TJ MacCormack, SG Lamarre, AV Sykes, WR Driedzic. 2017. Hypoxic induced decrease in oxygen consumption in cuttlefish (Sepia officinalis) is likely associated with decreases in protein synthesis and Na+/K+ ATPase. Frontiers in Physiology 8, 344.
  3. MJ Gallant, S LeBlanc, TJ MacCormack, S Currie. 2017. Physiological responses to short-term, environmentally realistic acute heat stress in Atlantic salmon, Salmo salar. FACETS 2: 330-341.
  4. NI Callaghan, TJ MacCormack. Review: Ecophysiological perspectives on engineered nanomaterial toxicity in fish and crustaceans. Comp. Biochem. Physiol. C in press.
  5. PT Gormley, NI Callaghan, TJ MacCormack, CA Dieni. Assessment of the toxic potential of engineered metal oxide nanomaterials using an acellular model: citrated rat blood plasma. Toxicol. Mech. Meth., http://dx.doi.org/10.1080/15376516.2016.1218986 http://www.tandfonline.com/doi/abs/10.1080/15376516.2016.1218986?journalCode=itxm20
  6. NI Callaghan, L Tunnah, S Currie, TJ MacCormack. Metabolic adjustments to short-term diurnal temperature fluctuation in rainbow trout (Oncorhyncus mykiss). Physiol. Biochem. Zool. 89: 498-510. http://www.journals.uchicago.edu/doi/abs/10.1086/688680
  7. L Tunnah, S Currie, TJ MacCormack. Do prior diel thermal cycles influence the physiological response of Atlantic salmon (Salmo salar) to subsequent heat stress? Can. J. Fish. Aquat. Sci., in press. http://www.nrcresearchpress.com/doi/abs/10.1139/cjfas-2016-0157#.V3_iyzWYJL8
  8. NI Callaghan, GJ Allen, TE Robart, CA Dieni, TJ MacCormack. 2016. Zinc oxide nanoparticles trigger cardiorespiratory stress and reduce aerobic scope in the white sucker, Catostomus commersonii. NanoImpact 2: 29-37. http://www.sciencedirect.com/science/article/pii/S2452074816300088
  9. JR Treberg, SS Killen, TJ MacCormack, S Lamarre, E Enders. Measuring metabolic rate in fishes under field conditions: methods, proxies, and new perspectives. Comp. Physiol. Biochem. A, special issue on field physiology, in press. http://www.sciencedirect.com/science/article/pii/S109564331630099X
  10. L Tunnah, SRC Mackellar, DA Barnett, TJ MacCormack, KM Stehfest, AJ Morash, JM Semmens, S Currie. Physiological responses to hypersalinity correlate with nursery ground usage in two inshore shark species (Mustelus antarcticus & Galeorhinus galeus). J. Exp. Biol. in press. http://jeb.biologists.org/content/early/2016/05/06/jeb.139964
  11. B Speers-Roesch, NI Callaghan, TJ MacCormack, S Lamarre AV Sykes, WR Driedzic. Enzymatic capacities of metabolic fuel use in cuttlefish (Sepia officinalis) and responses to food deprivation: insight into the metabolic organization and starvation survival strategy of cephalopods. J. Comp. Physiol. B in press.http://link.springer.com/article/10.1007/s00360-016-0991-3
  12. S Lamarre, TJ MacCormack, AV Sykes, JR Hall, B Speers-Roesch, NI Callaghan, WR Driedzic. Metabolic rate and rates of protein turnover in food deprived cuttlefish, Sepia officinalis (Linnaeus 1758). Am. J. Physiol. Reg. Integ. Comp. Physiol. In press. http://ajpregu.physiology.org/content/early/2016/04/01/ajpregu.00459.2015
  13. A Rundle, AB Robertson, AM Blay, KMA Butler, NI Callaghan, CA Dieni, TJ MacCormack. Cerium oxide nanoparticles exhibit minimal cardiac and cytotoxicity in the freshwater fish Catostomus commersonii. Comp Biochem Physiol C 181-182: 19-26. http://www.sciencedirect.com/science/article/pii/S1532045615001866
  14. TJ MacCormack, NI Callaghan, AV Sykes, WR Driedzic. 2015. Taurine depresses cardiac contractility and enhances systemic heart glucose utilization in the cuttlefish, Sepia officinalis. J Comp Physiol B 186: 215-227. http://link.springer.com/article/10.1007/s00360-015-0946-0
  15. PT Gormley, BN Khuong, CM Dickie, AM Taweel, HL Blundon, JEJ Melanson, AF LeBlanc, TS Murphy, CG Tompkins, CM Vogels, A Decken, FJ Baerlocher, TJ MacCormack, SA Westcott. 2015. Synthesis, characterization and antimicrobial properties of lipophilic palladium complexes bearing iminopyridine ligands. Transition Metal Chemistry 40: 813-819. http://link.springer.com/article/10.1007/s11243-015-9977-3
  16. TJ MacCormack, JL Robinson, VMF Almeida-Val, AL Val, WR Driedzic. 2015. Acclimation to hypercarbia protects cardiac contractility and alters tissue carbohydrate metabolism in the Amazonian armored catfish Ptergoplichthys pardalis. Hydrobiologia, special issue on Amazon Aquatic Biota, in press, accepted September 13, 2015. http://link.springer.com/article/10.1007/s10750-015-2496-6
  17. RJ MacLellan, L Tunnah, D Barnett, PA Wright, TJ MacCormack, S Currie. 2015. Chaperone roles for TMAO and HSP70 during hyposmotic stress in spiny dogfish shark (Squalis acanthias). J Comp Physiol B 185: 729-740.http://link.springer.com/article/10.1007/s00360-015-0916-6
  18. RA Bessemer, KMA Butler, L Tunnah, NI Callaghan, A Rundle, S Currie, CA Dieni, TJ MacCormack. 2014. Cardiorespiratory toxicity of environmentally relevant zinc oxide nanoparticles in the freshwater fish Catestomus commersonii. Nanotoxicology 9: 861-870. http://informahealthcare.com/doi/abs/10.3109/17435390.2014.982737
  19. KJ Ong, TJ MacCormack, RJ Clark, JD Ede, VA Ortega, LC Felix, MKM Dang, G Ma, H Fenniri, JGC Veinot, GG Goss. 2014. Widespread nanoparticle-assay interference: Implications for nanotoxicity testing. PLOS ONE 9: e90650.http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0090650
  20. CA Dieni, NI Callaghan, PT Gormley, KMA Butler, and TJ MacCormack. 2014. Physiological hepatic response to zinc oxide nanoparticle exposure in the white sucker, Catostomus commersonii. Comparative Biochemistry and Physiology C 162: 51-61. http://www.sciencedirect.com/science/article/pii/S1532045614000349
  21. KJ Ong, X Zhao, M Thistle, TJ MacCormack, RJ Clark, G Ma, Y Martinez-Rubi, B Simard, J Loo, JGC Veinot and GG Goss. 2013. Mechanistic insights into the effect of nanoparticles on zebrafish hatch. Nanotoxicology 8: 295-304. http://informahealthcare.com/doi/abs/10.3109/17435390.2013.778345
  22. CA Dieni, CJL Stone, ML Armstrong, NI Callaghan, and TJ MacCormack. 2014. Spherical gold nanoparticles impede the function of bovine serum albumin in vitro: a new consideration for studies in nanotoxicology. Journal of Nanomaterials and Molecular Nanotechnology 2:6.  http://www.scitechnol.com/ArchiveJNMN/currentissue-nanomaterials-molecular-nanotechnology.php
  23. A Schultz, KJ Ong, TJ MacCormack, G Ma, JGC Veinot, GG Goss. 2012. Silver nanoparticles inhibit sodium uptake in juvenile rainbow trout (Oncorhynchus mykiss). Environmental Science & Technology 46: 10295-10301. http://pubs.acs.org/doi/abs/10.1021/es3017717
  24. TJ MacCormack, R Clark, M Dang, J Kelly, JGC Veinot and GG Goss. 2012. Inhibition of enzyme activity by nanomaterials: potential mechanisms and implications for nanotoxicity testing. Nanotoxicology 6: 514-525. http://informahealthcare.com/doi/abs/10.3109/17435390.2011.587904
  25. JR Treberg, TJ MacCormack, JM Lewis, VMF Almeida-Val, AL Val and WR Driedzic. 2007. Intracellular glucose and binding of hexokinase and phosphofructokinase to particulate fractions increase under hypoxia in heart of the Amazonian armoured catfish (Liposarcus pardalis). Physiol. Biochem. Zool. 80: 542-550. http://www.jstor.org/stable/10.1086/520129
  26. TJ MacCormack and WR Driedzic. 2007. The impact of hypoxia on in vivo glucose uptake in a hypoglycemic fish, Myoxocephalus scorpius. Am. J. Physiol. 292: R1033-R1042. http://ajpregu.physiology.org/content/292/2/R1033
  27. TJ MacCormack, JM Lewis, VMF Almeida-Val, AL Val and WR Driedzic. 2006. Carbohydrate management, anaerobic metabolism, and adenosine levels in the armoured catfish, Liposarcus pardalis (Castelnau), during hypoxia. J. Exp. Zool. 305A: 363-375.  http://onlinelibrary.wiley.com/doi/10.1002/jez.a.274/abstract
  28. JR Hall, RC Richards, TJ MacCormack, KV Ewart and WR Driedzic. 2005. Cloning of GLUT3 cDNA from Atlantic cod (Gadus morhua) and expression of GLUT1 and GLUT3 in response to hypoxia. Biochimica et Biophysica Acta 1730: 245-252. http://www.sciencedirect.com/science/article/pii/S0167478105001855
  29. JR Hall, TJ MacCormack, CJ Barry and WR Driedzic. 2004. Sequence and expression of a constitutive, facilitated glucose transporter (GLUT1) in Atlantic cod (Gadus morhua). J. Exp. Biol. 207: 4697-4706. http://jeb.biologists.org/content/207/26/4697.long
  30. TJ MacCormack and WR Driedzic. 2004. Cardiorespiratory and tissue adenosine responses to hypoxia and reoxygenation in the short-horned sculpin Myoxocephalus scorpius. J. Exp. Biol. 207: 4157-4164. http://jeb.biologists.org/content/207/23/4157.long
  31. KA Clow, KJ Rodnick, TJ MacCormackand WR Driedzic. 2004. The regulation and importance of glucose uptake in the isolated Atlantic cod heart: rate-limiting steps and effects of hypoxia. J. Exp. Biol. 207: 1865-1874. http://jeb.biologists.org/content/207/11/1865.long
  32. TJ MacCormack and ME DeMont. 2003. Regional differences in allometric growth in the lobster Homarus americanus. J. Crust. Biol. 23: 258-264. http://www.jstor.org/stable/1549630
  33. TJ MacCormack, RS McKinley, R Roubach, VMF Almeida-Val, AL Val and WR Driedzic. 2003. Changes in ventilation, metabolism, and behaviour, but not bradycardia, contribute to hypoxia survival in two species of Amazonian armoured catfish. Can. J. Zool. 81: 272-280. http://www.nrcresearchpress.com/doi/abs/10.1139/z03-003#.UnKIGhCFfSg
  34. TJ MacCormack, JR Treberg, VMF Almeida-Val, AL Val and WR Driedzic. 2003. Mitochondrial KATP channels and sarcoplasmic reticulum influence cardiac force development under anoxia in the Amazonian armored catfish Liposarcus pardalis. Comp. Biochem. Physiol. 134A: 441-448. http://www.sciencedirect.com/science/article/pii/S109564330200315X
  35. TJ MacCormack and WR Driedzic. 2002. Mitochondrial ATP-sensitive K+ channels (KATP) influence force development and anoxic contractility in flatfish (Limanda ferruginea) but not cod (Gadus morhua) heart. J. Exp. Biol. 205: 1411-1418.http://jeb.biologists.org/content/205/10/1411.long